The Indianapolis Colts (11-5) and Buffalo Bills (13-3) lock horns in an AFC playoff game Saturday in NFL Wild Card Weekend at 1:05 p.m. ET at Bills Stadium. Below, we preview the Colts-Bills betting odds and lines and make our NFL picks and predictions.

Get the latest NFL odds, spreads and betting lines from this week's games, as well as full coverage of the National Football League from USA TODAY.

  • One of the best features on the NFL Vegas Odds is the Open Line. This numbers consists of the first betting line received from one of our Las Vegas or Global Sportsbooks. The opening line.
  • Our betting trends, also known as public betting percentages, represent actual wagers. A large money percentage indicates a higher likelihood that pros are betting on this side. Monitoring public betting data is a vital tool used by sharp bettors to find value within the sports betting marketplace.
  • A teaser is also another type of bet common among NFL bettors. In a teaser, a person can play two or more matches by changing the NFL lines. Most of the teasers let you adjust the point spread to 6 or 7 points, but let’s stick to the standard 6-point teaser matchup for now.
  • One of the best features on the NFL Vegas Odds is the Open Line. This numbers consists of the first betting line received from one of our Las Vegas or Global Sportsbooks. The opening line varies depending on the sportsbook but it provides a clear-cut rating that the oddsmakers use.

Colts at Bills: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 4:04 a.m. ET.

Money line: Colts +230 (bet $100 to win $230) Bills -275 (bet $275 to win $100)Against the spread/ATS: Colts +6.5 (-105) Bills -6.5 (-115)Over/Under: 51.5 (O: -105 U: -115)

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Colts at Bills: Game notes

The Colts enter this game having won four of their past five games outright, but they’re 0-3 ATS since their most recent cover in Week 14 in Las Vegas. Indianapolis has also scored at least 24 points in each of its past eight games.Indianapolis has racked up 378.1 total yards of offense per game to rank 10th in the NFL, and they’re 11th in both passing yards (253.3) and rushing yards (124.8) per contest. The Colts rank ninth with 28.2 PPG.Defensively the Colts have been stout, allowing just 332.1 total yards per game to rank eighth in the NFL, and they’re second in rushing defense with 90.5 yards per game allowed. If teams have success against their D, it’s through the air, as they have allowed 241.6 passing yards per game to check in just 20th.Buffalo scored a season-high 56 points in their 30-point win over Miami in Week 17, winning for the sixth straight game, while covering for the eighth consecutive outing. They have also won five straight at home and covered four in a row in Western New York.The Bills’ offense has been on point, going for 396.4 total yards per game to rank second in the NFL. They’re also second in points scored, 31.3 PPG while averaging 288.8 passing yards per game to rank third in the league. If they have an Achilles heel, it’s their run game, which generated just 107.7 rushing yards per contest.

Colts at Bills: Key injuries


DT DeForest Buckner (ankle) questionableCB Rock Ya-Sin

Nfl Gambling Line

(concussion) out


WR Cole Beasley (knee) questionableWR Stefon Diggs (oblique) questionable

Colts at Bills: Odds, betting lines, predictions and picks


Bills 29, Colts 20

Money line (?)

Nfl betting lines doc sportsHow to read nfl sports betting lines

Playing the Bills (-275) is not a good idea, risking nearly three times your potential return. Over the long haul, it’s a losing proposition to bet in that manner unless you plan to toss it into a multi-team parlay. Even then, it’s better to just bet against the spread. PASS.

Against the spread (?)

The BILLS -6.5 (-115) have been money at home, with their last non-cover coming in Week 8 against New England in a 24-21 win as four-point favorites, and their last outright loss coming in Week 10 against the Arizona Cardinals on the Hail Murray, 32-30.

Even without their throngs of fans at full throat, Bills Stadium has been a difficult place to play. They’ll have a limited amount of fans in the stands Saturday to help spur them on.

Nfl Sports Betting Lines

Over/Under (?)

These are a couple of high-flying offenses, and they should put on a show in the opening game of the 2020 NFL playoffs. However, the lean is to the UNDER 51.5 (-115).

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In last season’s wild-card round the Under was a perfect 4-0, and the Under is hitting at a 75.8 percent clip (22-7-3) across the wild-card round in the past eight seasons. That’s good enough for me to keep banging Under plays.

Want action on this NFL game? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit Please gamble responsibly.

Also see:

Bet Slippin’ PodcastColts’ Ryan Kelly, Luke Rhodes named second-team All-Pro (Colts Wire)Bills vs. Colts: 3 key matchups in Wild Card (Bills Wire)

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There are many ways to bet sports. If you can think of anything to bet on, there's a good possibility you can find somewhere to pick on it. In this document on the different terms used in sports betting lines, including probabilities point spreads lines etc. One of the first aspects of sports betting every new player must learn what the different symbols mean. A plus or minus can mean different things and furious situation. They are used for both point spreads and money line bets, including the price of each jet. A point spread is the number of points projected that separate two teams. A game with a spread will have an underdog (team expected to lose) and a favorite (team expected to win). A favorite 'gives' points and is identified with the negative signs next to the point spreads. The underdog 'gets' points. The spreads happen this way in the gambling of games.

College Football, Baseball and Basketball Betting Odds

A money line bet is on a team to win the game outright (with no point spread) at an adjusted cost. The favorite will have negative odds, while the underdog will have positive odds. The difference here is in the prize or payout, depending on which topic. The terms 'over/under' are synonymous when placing wagers. This type of bet is on the sum of the points scored by both teams in a game. The bookie sets the number for the total then you predict whether they will score less or more points than the set number. For basketball and football, the primary display will show the total and points spread. For baseball and hockey, the money lines appear before it is displayed along with the total of the game, more so happens in hockey.

How To Read Nfl Sports Betting Lines

Hockey Stanley Cup and Football Super Bowl Point Spreads

Understanding NFL football betting odds & weekly point spread is important. If you plan on NFL football picks, this document will be of essence. It's imperative to use live NFL odds for every spread, total and money line for the games in a given week. If the number is positive, then you bet $100 to win that amount. If the number is negative, you have to wager that amount to win $100.Sometimes it will be necessary to use a conversion chart to translate the money lines to take advantage of the betting opportunities that spreads in a week.

Nfl Sports Betting Lines

CFB and WNBA Playoff Picks, Nascar and PGA Golf Bets

Cbs Sports Nfl Betting Lines

NBA scoring pace calculator for over and under bets can feel complicated at times. When you bet an NBA total and want to know the current pace of play, you will need to use a calculator to estimate the NBA final score quickly. This tool is useful if you want to know how your basketball over-under bet is looking or if you want to take advantage of the bets opportunities spreads. The same applies to the super bowl and Stanley cup. Without 162 game season per team and 30 teams, MLB is the ultimate sports action for sports gaming. The best MLB betting sites include Betway and Spin palace sports. It is no secret that many people crush bet on MLB, as it has most of the experts.

Vegas Line On Nfl Games

Soccer Odds, British Open Championship and Premier League Betting Lines

Nfl Playoff Las Vegas Lines

Betting is also done in soccer. Many teams are even sponsored by bookmaking companies. Soccer is one of the most popular sports in the world. At the moment, this is true in the United States. Soccer picks are not overly difficult, even for beginners. You have to decide on which markets to put on focus. There are different markets to welcome, including major domestic leagues such as La Liga Serie A and Bundesliga e t c.

MMA UFC and College Basketball Week

The advantage of major domestic leagues is that they offer soccer picks advantages. These include:
  • Attacking players are in good form
  • You can set-piece specialist
  • Defenders like to get forward at set-pieces
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